Lifelong endurance training attenuates age-related genotoxic stress in human skeletal muscle

Longevity & Healthspan

Table 1 Mean (SD) characteristics of the four subject groups

	Young trained	Young untrained	Old trained	Old untrained	Group Pvalue
Age (years)	24.2 (3.6)†	22.1 (3.4)†	64.5 (5.5)^a	63.8 (3.0)^a	0.001
Height (cm)	177 (8.6)	182 (6.5)	175 (6.8)	175 (9.3)	0.786
Mass (kg)	66.2 (10.0)	84.5 (10.8)	71.8 (7.8)	95.5 (24.8)^ab	0.037
Lean mass and BMC (kg)	59.3 (6.3)	66.7 (8.9)	59.8 (7.4)	66.1 (6.8)	0.127
Fat mass (kg)	6.9 (1.5)	17.8 (2.1)^a	12 (6.4)^a	29.41 (12.3)^abc	0.001
Body Fat (%)	10.5 (1.5)	21.1 (2.1)^a	16.7 (1.8)^a	30.8 (11.5)^abc	0.001
VO_2max (ml.kg^-1.min^-1)	64 (7.0)	42 (4.1)^a	47 (8.3)^a	28 (9.8)^abc	0.001

^adenotes significant difference from young trained; ^bdenotes significant difference from young untrained; ^cdenotes a significant difference from old trained. BMC = bone mineral content.